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Presentation and composition: Boxes of 10, 60 and 500
sustained release film-coated tablets dosed at 1.5 mg of
Excipients: q.s.f one tablet.
Indications: This drug is prescribed for the treatment of essential
Contra-indications: Do not take NATRILIX SR in the following
 known allergy to this drug or to sulphonamides,
 renal failure,
 serious hepatic disease,
 hypokalemia (abnormally low blood potassium level).
If in any doubt, you must ask advice from your doctor or
Precautions for use: The administration of the drug should be
stopped if hepatic disease develops.
Due to the presence of lactose, this drug should not be used if the
patient has galactosemia, glucose or galactose malabsorption
syndrome or a lactase deficiency (rare metabolic diseases).
Use this drug CAUTIOUSLY in the case:
 Disturbed water/electrolyte balance, diabetes, gout, kidney
Your doctor may advise you to undergo laboratory tests to monitor
your treatment.
Athletes: The attention of athletes is drawn to the fact that this
drug contains an active ingredient that may induce a positive
reaction during anti-doping control tests.
If in doubt, do not hesitate to consult your doctor or pharmacist.
Pregnancy – Lactation: The use of this drug is contraindicated
during breast-feeding.
In general, it is advisable during pregnancy and breast-feeding to
always consult your doctor or pharmacist before taking any drug.
Drivers and machine operators: Individual reactions can occur
in certain patients due to a reduction in blood pressure.
Consequently, the ability to drive or use machinery may be
List of excipients with a known effect: lactose
Interactions with other medicines and other forms of
interactions: Please tell your doctor or your pharmacist if you
are taking or have recently taken another drug, particularly
lithium, even if this involves a drug that was obtained without
a prescription.
Dosage and method of administration: Oral route.
One tablet daily. The tablet should be swallowed with water
and should not be chewed.
In all cases, strictly comply with your doctor’s prescription.
If you think that the effect of NATRILIX SR is too potent or too
weak, consult your doctor or pharmacist.
Frequency of administration
A single administration every 24 hours, preferably in the
morning on account of the diuretic effect of this drug in order
to avoid possible waking during the night.
Duration of treatment
Always strictly comply with your doctor’s prescriptions.
Course of action to take when one or more doses have been
Do not take a double dose to compensate for the single dose
that you forgot to take.
Overdosage: Consult your doctor or pharmacist immediately.
Undesirable effects: Like any drug, NATRILIX SR can have
undesirable effects:
 feeling of fatigue (asthenia), headache, pins and
needles affecting the extremities,
 allergic-type symptoms, rare cases of skin rashes,
 a feeling of dizziness when changing from a lying to a
standing position,
 risk of dehydration increased in the elderly and in heart
failure patients,
 nausea, constipation, dry mouth,
 changes in blood parameters can occur, particularly an
excessive fall in potassium, especially in the elderly or
malnourished individuals.
Your doctor may ask you to undergo laboratory tests to
monitor these parameters.
If you experience any undesirable effect not mentioned in this
leaflet, please tell your doctor or pharmacist.
Storage conditions:
Below 30oC.
Keep out of reach and sight of children.
Do not take after the expiry date printed on the box.
Les Laboratoires Servier – France
Manufacturer :
Les Laboratoires Servier Industrie
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